Drought is a natural phenomenon as it often occurs in the area of Yasothon province, northeastern of Thailand. It causes effects on vegetation condition in the area. Drought information might be useful for local government to prepare for prevention and mitigation plan in the future. For this reason, the primary objective of the research was to conduct the examination of this province to find severe drought years. Firstly, the researcher needed to find Normalized Differences Vegetation Index (NDVI) and Vegetation Condition Index (VCI) by analyzing monthly Landsat data acquired at different periods of time from January to December 2014, 2015, and 2016, covering 4,096 km2. Then, the researcher needed to find relationship between VCI and monthly rainfall represented in term of space and time. As results, VCI and its relationship with monthly rainfall were congruent. VCI showed that the drought area was 33.87% or 1,387.32 km2 of studied area in 2014, 16.24% or 665.19 km2 of studied area in 2015 and 27.95% or 1,144.83 km2 of studied area in 2016. Therefore, the most and the least severe drought years were 2014, 2016, and 2015 respectively.