Cytotoxic Test of Octopus cyanea Ink Extract
John Dominggus Kalor 1  
,   Eva Susanty Simaremare 1  
,   Gloria Wabiser 1  
,   Allowisya Futwembun 1  
,   Elsye Gunawan 1  
,   Yuliana Rut Yabansabra 1  
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Cenderawasih University
John Dominggus Kalor   

Cenderawasih University
Publication date: 2019-09-01
J. Ecol. Eng. 2019; 20(8):144–152
Marine biodiversity of Papua is very high, but unfortunately research and utilization in medicine are limited. Many species of flora and fauna are used in ethopharmacology as drugs but without scientific explanation, e.g. octopus (Octopus cyanea), found in the Northern Papua Sea. The aim of this research was to test the toxicity of the ethanol octopus ink. The toxicity was tested with the Brine Shrimp Lethality Test (BSLT) method. The samples were collected from the sea of Biak island in West Papua, extracted with ethanol, ethyl acetate, and dichloromethane then tested the toxicity for Artemia salina leach larvae. The toxicity test involved concentrations of 1000, 750, 500, 250, 100, 75, 50, and 25 ppm. The result showed that ethanol extract of octopus ink has LC50 of 290 ppm, ethyl acetate extract has LC50 of 947 ppm, whereas dicholoromethane extract – 2190 ppm.