High technology application in agricultural production is an inevitable trend in today's society. In Vietnam, high-tech agricultural production has developed for a long time in high-tech industrial park production. However, in agricultural production, applying high technology with mass production has yet to have any specific regulations on criteria for implementation in production. On that basis, the research aimed at determining the requirements for developing high-tech agriculture with mass production. Therefore, the predefined criteria for primary and secondary data were developed, which were used for the data collected from farmers, managers, and scientists. Thereby, a production hierarchy of adaptations for rice and corn was built based on consultation results with the farmers and scientists and published studies. The results also made three land adaptation zones apply high technology in mass production for these two crops. The areas suitable for producing rice and corn with high technology applications were marginally suitable, and not suitable prevailed. No region in the An Giang province has a strong potential for cultivating high-tech rice and corn. This result also established adaptive upgrading solutions for applying high technology in the future, which helped improve agricultural production efficiency.