Open dumpsites have been identified as significant sources of air emissions. This study analyzed the spatial and temporal variations of multicomponents in the Sarimukti dumpsite, Indonesia, and the health profiles of landfill workers. The analysis revealed that benzene, PM2.5, and NH3 levels exceeded the permissible threshold, with average value of 0.41 ppm, 103.2 μg/m3, and 1.26 ppm, respectively. H2S and meteorological factors were strongly correlated. The absence of daily soil cover and vehicle activity at the dumpsite contributed to the ambient air quality issues at the Sarimukti dumpsite. Further studies are necessary to assess the long-term health risks to dumpsite workers.