The application of sewage sludge as a fertilizer in podzols soil ambiguously affects the peculiarities of the accumulation of certain chemical elements in various organs of Jerusalem artichoke plants. Experimental factors in the study were different doses of sewage sludge from sludge maps of sewage treatment plants and its compost with cereal straw, included together with the compensatory dose of mineral fertilizers to the norm N90P90K90 in the Jerusalem artichoke plantation. Determination of the content of chemical elements in soil and plants was carried out by X-ray fluorescence analysis. According to the results of research it is established that the change of mineral nutrition conditions of Jerusalem artichoke causes significant changes in the chemical composition of its tubers and vegetative mass. Studies have shown a clear positive effect of increasing doses of SS on increasing the content in tubers: K - to 7.9%, Ca - to 1.9, Fe - to 1.9, in green mass: O - to 31.8%, K - to 31.6, Ca - to 24.9, Mg - to 5.9, Mn - to 0.7, Fe - to 0.4 and K - to 34.5%. The coefficients of biological absorption for most chemical elements are more than 1, but for O, Al, Si, Fe, these figures were less than 1. Regression models of phosphorus, potassium, calcium and magnesium content in the vegetative mass of Jerusalem artichoke indicate a high and moderate dependence of these indicators on their content in Jerusalem artichoke tubers and soil.