The aim of studies was to evaluate an effect of oxidizing agents on degradation of 2-ethylhexyl 4-(dimethylamino)benzoate (ODPABA). The oxidation reaction was carried out in the presence of oxidizing agents used for disinfection of water and treatment of sewage containing organic pollutants. Oxidants such as: sodium hypochlorite, hydrogen peroxide or ozone with UV radiation. ODPABA degradation and analysis of products were performed using gas chromatograph coupled with mass spectrometry detector. The most effective solution was the use of sodium hypochlorite and UV radiation. As a result, halogenoorganic products are formed. It is likely that the resulting by-products can be more toxic than the initial substrate. In the case of ozone and hydrogen peroxide, it was shown that these agents are characterized by weaker oxidative activity and therefore, fewer metabolites are formed.