Water and land pollution is a major environmental problem. One treatment system that is suitable for use in many parts of the world is wastewater treatment from Artificial Wetlands. The sample source came from the Aur River, Palembang City. The vegetation used consists of water spinach, water hyacinth and lotus. This research aims to determine the influence of Constracted Wetlands; know the differences in length of treatment; determine the differences in the effectiveness of kale, water hyacinth and lotus vegetation, and calculate the percentage reduction in concentration after treatment. The results of the research showed that the results of the analysis of the influence before and after the CW intervention on three vegetation on the parameters BOD, COD, DO, Oil and Fat, Detergent, Ammonia, and total coliform obtained the same P value, namely 0.000, meaning there was a significant influence on concentration before and after CW intervention was carried out. The results of the analysis of differences in concentration in the three vegetation groups in week -1, week -2, week -3 and week -4 on the parameters BOD, COD, DO, Oil and Fat, Detergent and Ammonia obtained the same P value, namely 0.000 (< 0.05) means that there is a significant difference in concentration after the CW intervention, while the total coliform in the three vegetation groups was found to be kale vegetation 0.979 (> 0.05), water hyacinth vegetation 0.972 (> 0.05) and lotus vegetation 0.971 (> 0, 05) means there is no significant difference in concentration. The results of the analysis of kale, water hyacinth and lotus vegetation of the horizontal CW type showed that the P value of BOD, COD and DO was the same, namely 0.000, (< 0.05) meaning there was a difference, while the parameters Oil and Fat = 0.888, Detergent = 0.945 , Ammonia = 0.902 and total coliform = 0.977 (> 0.05) meaning there is no difference. Apart from that, there was also a decrease in concentration before and after the Constracted Wetlands intervention. Each vegetation group. In water spinach vegetation, it is between 86,36%-562,50%, water hyacinth is between 91,30%-737,50%, and lotus is between 91,30%-737,50%.