This study aimed to determine the performance of modified slow sand filter (SSF) media with blood clam shells (Anadara granosa) and activated carbon to remove turbidity, TSS, TDS, and FOG on the food court wastewater. The concentration of water pollutant parameters processed by SSF was determined based on Indonesia water quality standards, as well as knowing the optimum operational parameters of intermittent slow sand filter with Response Surface Methodology (RSM). The research data was processed using the Optimal type (custom) design which consisted of independent factors including the type of filter media, the addition of bacteria to the grease trap pre-treatment unit, and running time, as well as the research response in the form of the effectiveness of removing turbidity, TSS, TDS, and FOG. The reactor was operated intermittently (48 hours) for a maximum of 22 days and the concentration of pollutant parameters was calculated using the Standard Methods. The results of the Analysis of Variance (ANOVA, p<0.05) in the 2FI model of the study showed that there was a significant effect of all independent factors on the effectiveness of removing all water pollutant parameters. The most optimal operational parameters were achieved with the type of activated carbon media, the addition of Bacillus sp. in the grease trap pre-treatment unit in the amount of as much as 1%, and the detention time of 4 days, with the effectiveness of removing turbidity reaching 39.53%; TSS 45.25%; TDS 19.30%; FOG 61.35%.