The article is devoted to a study of the issues related to the processes of reducing the greenhouse gas emissions using different types of biofuels. The dynamics of carbon dioxide emissions in the global energy sector were analyzed and it was determined that a stable level of the CO2 emissions in the last three years is due to introduction of the technologies with the use of renewable energy sources by developed countries. It was proven that the assessment of total greenhouse gas emissions requires an analysis of emissions throughout the life cycle of a biofuel. The impact of a biofuel on the climate change depends on the raw material from which it is produced, and which has a decisive influence on its chemical composition and performance. It was established that a significant role in ensuring energy security and preventing climate change is attributed to the development of biotechnologies, unrelated to the risks of agricultural production. The use of a biofuel from lignocellulose raw material may be more efficient in terms of reducing the greenhouse gas emissions. A biofuel, obtained from the processing of microalgae, also has important prospects. The ability of microalgae to bind atmospheric carbon dioxide may have a positive effect on solving the problem of greenhouse effect.