As the main purpose of this article, the authors consider the level of soil pollution in the Aksu River basin as a result of anthropogenic impact, in which factors of anthropogenic transformation of soils in different zones play an important role, as well as processes occurring in soils as a result of their impact. This article highlights the research of the main analyses carried out, which showed that the anthropogenic transformation of soils within the surveyed territory is multifactorial and complex. As an assumed result, the validity of which is analyzed in this article, it can be considered that the degree and forms of manifestation of anthropogenic transformation of foothill soils depend on their use, as one criterion of which is considered the use of such soil for arable land, including irrigated arable land, in which the degradation of mountain soils is mainly associated with pasture loads during a certain period. As a research question, it remains to be considered whether this is really the case or whether the present territory is subject to a different anthropological impact.