The purpose of the work was to determine the efficiency of domestic sewage treatment contaminated with a mixture of pesticides at varying deposit load. Efficiency of purification in the case of eight pesticides was 99.8%, and the removal effect of azoxystrobin reached 93%, while that of thiachloprid - 96%. The constructed wetland ensured high removal of organic matter expressed as BOD and COD, as well as reduction in the concentration of nitrogen and phosphorus compounds. Studies showed a clear impact of the deposit load on the effectiveness of pesticide removal, BOD and COD parameters, total phosphorus, and total nitrogen.