Artisanal and Small-Scale Gold Mining (ASGM) in Tanzania is an important sector, employing over 1.5 million people. Despite the profound benefits, the activity is associated with environmental contamination by the release of heavy metals, which affects soil quality and public health. Therefore, this study was conducted to assess the potential of locally adapted plants to remove heavy metals in contaminated soils around the Lupa Goldfield, Chunya District, in the Mbeya region. A total of 50 soil samples and 19 plant species were collected from mining tailings at depths of 0–200 m across five villages (Chokaa, Makongolosi, Itumbi, Matundasi, and Mbugani). Atomic Absorption Spectroscopy (AAS) was used to quantify the concentrations of Pb, Hg, Cd, As, and Zn in both soil and plant samples. Plant specimens were identified and deposited in the NM-AIST Herbarium for reference. Mean soil concentrations at the tailing heaps were 40.73 ± 0.5 mg kg-1 for Pb, 3.17±0.14 mg kg-1 for Hg, 4.36 ± 0.25 mg kg-1 for Cd, 1.69 ± 0.02mg kg-1 for As and 24.9 ± 0.54mg kg-1 for Zn declining sharply to 17.48 ± 0.64 mg kg-1 (Pb), 1.03 ± 0.23mg kg-1 (Hg), and 0.16 ± 0.05 mgkg-1 (Cd), 0.27 ± 0.01 mgkg-1 (As) and 5.99 ± 0.54 mgkg-1 (Zn) at 200 m (p < 0.05), confirming significant point-source pollution. The highest concentrations of heavy metals were recorded in the following plant species: Pb =1.71mgkg-1 in Urochloa mutica, (Hg=1.38 ± 0.2 mg kg-1) in Schonocleptus corymbosus, (Cd=1.05 ± 0.05 mg kg-1) in Bauhinia petersiana, (As= 0.9 ± 0.01 mg kg-1) in U. mutica and Zn=4.2 ±0.2 mg kg-1 in U. trichopus. On remediation potential, U. mutica, B. petersiana, Cyperus rotundus, Cariniana estrellensis and Cymbopogon giganteus (BAF>1 and TF>1) were identified as potential remediators for As. while B. petersiana, C. giganteus and Terminalia sambesiasca (BAF>1 and TF>1) were found to be good remediators for Cd. Schoenoplectus corymbosus (BAF>1 and TF>1) was found to be a good remediator for Hg. These findings provide a quantitative basis for integrating the identified plant species into low-cost ecological restoration strategies in ASGM-impacted landscapes in the Lupa gold field.