Medicinal and aromatic plants are widely used in pharmaceutical, food and cosmetic products, so their chemical safety and quality are essential to ensure therapeutic efficacy and protect consumer health. This study evaluated the concentration of selected trace and potentially toxic elements in two commonly used medicinal plants, Origanum vulgare L. and Salvia officinalis L., collected from different regions of Albania. Twelve samples were analysed for cadmium (Cd), nickel (Ni), chromium (Cr), aluminium (Al), lead (Pb) and copper (Cu). Elemental determination was performed using graphite furnace atomic absorption spectrometry (GF-AAS), after microwave-assisted digestion following the USEPA 3052 protocol, with quality assurance procedures in accordance with internationally accepted guidelines for medicinal plant analysis. The results indicated that most of the analysed samples complied with the permissible limits established by FAO/WHO for heavy metals in medicinal plants. Al was the most abundant element in both species, with concentrations ranging from 43.96 mg/kg to 213.23 mg/kg in S. officinalis and from 34.14 mg/kg to 129.14 mg/kg in O. vulgare. Although elevated, aluminium levels likely reflect natural geogenic origin rather than anthropogenic contamination. Cu and Cr were detected at moderate concentrations (Cu: 3.57–4.25 mg/kg and Cr: 1.23–7.85 mg/kg in S. officinalis; Cu: 4.32–7.29 mg/kg and Cr: 0.27–1.81 mg/kg in O. vulgare), remaining within acceptable limits. Pb and Cd were present only at trace levels in all analysed samples. Ni levels exceeded the recommended limit in both S. officinalis (1.09–7.47 mg/kg), and O. vulgare samples (1.73–7.41 mg/kg), suggesting a possible contamination of the plants. The non-carcinogenic risk assessment, based on Target Hazard Quotient (THQ) and Hazard Index (HI), showed values well below the safety threshold, with a resulting HI of 0.096 for S. officinalis and 0.055 for O. vulgare. Therefore, from a pharmaceutical safety perspective, these results suggest a low estimated non-carcinogenic risk under the defined exposure conditions.